ICD   PCS   Disclaimer
ICD-10-CM-2023 Diagnosis Codes Overview
ICD-10-CM-2023 > D50-D89 > D80-D89 > D89
D80-D89
Certain disorders involving the immune mechanism
Incl.:
defects in the complement system
immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
sarcoidosis
Excl1.:
autoimmune disease (systemic) NOS (M35.9)
functional disorders of polymorphonuclear neutrophils (D71)
human immunodeficiency virus [HIV] disease (B20)
D89

Other disorders involving the immune mechanism, not elsewhere classified

Excl1.:
hyperglobulinemia NOS (R77.1)
monoclonal gammopathy (of undetermined significance) (D47.2)
Excl2.:
transplant failure and rejection (T86.-)
D89.0
Polyclonal hypergammaglobulinemia
Info:
Benign hypergammaglobulinemic purpura
Polyclonal gammopathy NOS
D89.1
Cryoglobulinemia
Info:
Cryoglobulinemic purpura
Cryoglobulinemic vasculitis
Essential cryoglobulinemia
Idiopathic cryoglobulinemia
Mixed cryoglobulinemia
Primary cryoglobulinemia
Secondary cryoglobulinemia
D89.2
Hypergammaglobulinemia, unspecified
D89.3
Immune reconstitution syndrome
Info:
Immune reconstitution inflammatory syndrome [IRIS]
Use add'l
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
D89.4

Mast cell activation syndrome and related disorders

Excl1.:
aggressive systemic mastocytosis (C96.21)
congenital cutaneous mastocytosis (Q82.2)
(non-congenital) cutaneous mastocytosis (D47.01)
(indolent) systemic mastocytosis (D47.02)
malignant mast cell neoplasm (C96.2-)
malignant mastocytoma (C96.29)
mast cell leukemia (C94.3-)
mast cell sarcoma (C96.22)
mastocytoma NOS (D47.09)
other mast cell neoplasms of uncertain behavior (D47.09)
systemic mastocytosis associated with a clonal hematologic non-mast cell lineage disease (SM-AHNMD) (D47.02)
D89.40
Mast cell activation, unspecified
Info:
Mast cell activation disorder, unspecified
Mast cell activation syndrome, NOS
D89.41
Monoclonal mast cell activation syndrome
D89.42
Idiopathic mast cell activation syndrome
D89.43
Secondary mast cell activation
Info:
Secondary mast cell activation syndrome
Use add'l
underlying etiology, if known
D89.44
Hereditary alpha tryptasemia
Use add'l
code, if applicable, for:
allergy status, other than to drugs and biological substances (Z91.0-)
personal history of anaphylaxis (Z87.892)
D89.49
Other mast cell activation disorder
Info:
Other mast cell activation syndrome
D89.8

Other specified disorders involving the immune mechanism, not elsewhere classified

D89.81
Graft-versus-host disease
Code first
underlying cause, such as:
complications of transplanted organs and tissue (T86.-)
complications of blood transfusion (T80.89)
Use add'l
code to identify associated manifestations, such as:
desquamative dermatitis (L30.8)
diarrhea (R19.7)
elevated bilirubin (R17)
hair loss (L65.9)
D89.810
Acute graft-versus-host disease
D89.811
Chronic graft-versus-host disease
D89.812
Acute on chronic graft-versus-host disease
D89.813
Graft-versus-host disease, unspecified
D89.82
Autoimmune lymphoproliferative syndrome [ALPS]
D89.83
Cytokine release syndrome
Code first
underlying cause, such as:
complications following infusion, transfusion and therapeutic injection (T80.89-)
complications of transplanted organs and tissue (T86.-)
Use add'l
code to identify associated manifestations
D89.831
Cytokine release syndrome, grade 1
D89.832
Cytokine release syndrome, grade 2
D89.833
Cytokine release syndrome, grade 3
D89.834
Cytokine release syndrome, grade 4
D89.835
Cytokine release syndrome, grade 5
D89.839
Cytokine release syndrome, grade unspecified
D89.89
Other specified disorders involving the immune mechanism, not elsewhere classified
Excl1.:
human immunodeficiency virus disease (B20)
D89.9
Disorder involving the immune mechanism, unspecified
Info:
Immune disease NOS

 

ICD-10-CM-2023 Code Search Engine and PCS-2023 Code Search Engine